Controlled Release of Perfumes from Polymers. II. Incorporation and Release of Essential Oils from Glassy Polymers
نویسندگان
چکیده
Release of essential oils from glassy hydrophilic copolymers of 2-hydroxyethyl methacrylate (HEMA) and ethylene glycol dimethacrylate (EGDMA) was studied in a range of releasing media at 307C. The release of carvone, limonene, and eugenol was investigated using swelling-controlled release systems based on these copolymers. By changing the crosslinking ratio of the copolymers it was possible to achieve zeroorder release. The amount of essential oil release was correlated to the thermodynamic compatibility of the oil–polymer pair, as judged by the solubility parameter difference. q 1997 John Wiley & Sons, Inc. J Appl Polym Sci 66: 509–513, 1997
منابع مشابه
In Situ Cross-Linking of Polyanionic Polymers to Sustain the Drug Release from Theophylline Tablets
The aim of this study was to develop an extended-release tablet formulation using a new in situ cross-linking method. The effects of polyvalent cations on theophylline release from tablets made with the polyanionic polymers sodium alginate and sodium carboxymethylcellulose, were investigated. Different miliequivalents of the di and tri-valent cation, Ca2+ and Al3+, were added to tablet form...
متن کاملIn Situ Cross-Linking of Polyanionic Polymers to Sustain the Drug Release from Theophylline Tablets
The aim of this study was to develop an extended-release tablet formulation using a new in situ cross-linking method. The effects of polyvalent cations on theophylline release from tablets made with the polyanionic polymers sodium alginate and sodium carboxymethylcellulose, were investigated. Different miliequivalents of the di and tri-valent cation, Ca2+ and Al3+, were added to tablet form...
متن کاملDevelopment and Evaluation of Thymol Microparticles Using Cellulose Derivatives as Controlled Release Dosage Form
Thymol, an important and advantageous component of many essential oils, has been applied as an antimicrobial agent in animals. To increase the duration of action of this compound in ruminants, it was decided here to prepare a controlled release carrier for thymol. Hydroxy propyl methyl cellulose (HPMC) and ethyl cellulose (EC) were used as the matrix polymer here. Mixtures of thymol with eight ...
متن کاملDevelopment and Evaluation of Thymol Microparticles Using Cellulose Derivatives as Controlled Release Dosage Form
Thymol, an important and advantageous component of many essential oils, has been applied as an antimicrobial agent in animals. To increase the duration of action of this compound in ruminants, it was decided here to prepare a controlled release carrier for thymol. Hydroxy propyl methyl cellulose (HPMC) and ethyl cellulose (EC) were used as the matrix polymer here. Mixtures of thymol with eight ...
متن کاملHydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide
Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...
متن کامل